You must wait at least 24 hours after Spravato before driving
Spravato (esketamine) causes dissociation, dizziness, and impaired judgment that can last for hours. The FDA mandates a minimum 24-hour no-drive rule post-treatment due to sedation risks. Patients must arrange transportation home and avoid operating machinery until fully recovered, typically the next day.
Why You Can't Drive After Spravato
- Cognitive impairment: Alters reaction time, focus, and decision-making for 4-12+ hours.
- Dissociation/sedation: May feel "detached" or dizzy, increasing accident risk.
- Blood pressure spikes: Can cause lightheadedness or fainting.
- Legal liability: Driving under the influence of ketamine-like drugs may violate laws.
Recovery Timeline: When Can You Drive?
| Time After Treatment | Symptoms | Driving Risk | Recommended Activity |
|---|---|---|---|
| 0-2 hours | Peak dissociation, dizziness, nausea | ❌ Extremely high | Rest under supervision; no physical exertion |
| 2-8 hours | Mild sedation, slowed reflexes | ⚠️ High | Avoid complex tasks; no driving |
| 8-24 hours | Residual fatigue, possible mood shifts | ⚠️ Moderate | Light activities; assess readiness with a healthcare provider |
| 24+ hours | Symptoms typically resolved | ✅ Low (if cleared) | May drive if no lingering effects and approved by clinician |
Safety Checklist Before Driving
- Wait 24 hours: No exceptions, even if you "feel fine."
- Consult your provider: Confirm no adverse reactions during treatment.
- Test reflexes: Practice simple tasks (e.g., walking straight, balancing) without dizziness.
- Avoid alcohol/other sedatives: These prolong impairment.
- Start with short trips: Drive in low-traffic areas first to gauge readiness.
Alternatives to Driving Post-Treatment
- Pre-arranged ride: Use a friend, family member, or ride-share service.
- Public transit: Only if accompanied and symptoms are fully resolved.
- Taxi/medical transport: Some clinics offer coordinated services.
- Walk/bike: Only if short-distance and no dissociation risk remains.
What If You Drive Too Soon?
- Accident risk: Impaired driving increases collisions, injuries, or fatalities.
- Legal consequences: Could face DUI charges if pulled over.
- Treatment disruption: Clinics may discontinue therapy for non-compliance.
- Worsened side effects: Stress from driving may exacerbate dissociation or anxiety.